Anxious Depression Treatment

Deep Transcranial Magnetic Stimulation (Deep TMS™) is the FIRST TMS system FDA-cleared to safely and effectively reduce comorbid anxiety symptoms in adult patients with depression, also known as anxious depression.

Deep TMS treatment utilizes magnetic pulses generated by Capote TMS LLC patented H1 Coil to stimulate neurons in areas of the brain associated with anxious depression, including the dorsolateral prefrontal cortex (DLPFC) – particularly the left side.

Multiple peer-reviewed clinical studies have found Deep TMS to be a highly effective treatment in treating anxiety comorbid with depression. In a multicenter, double-blind controlled study, Deep TMS showed significant reductions in anxiety symptoms through the acute course of TMS treatments and retained improvement through 16 weeks.

As a noninvasive procedure, Deep TMS is a well-tolerated treatment that does not cause any adverse or long-lasting side effects. It does not require a significant recovery period, and the 20-min treatment can easily be integrated into each patient’s day-to-day schedule.

Anxious Depression: Key Points

Anxious Depression refers to anxiety symptoms in patients suffering from Major Depressive Disorder (MDD). It affects approximately 10-16 million adults in the United States each year. This is distinct from patients that experience depression that is triggered by a primary diagnosis of an anxiety disorder, such as generalized anxiety disorder or panic disorder.

Both anxiety and depression have been associated with experiencing distress when facing the unknown. For depression, the trigger is related to a sense of sadness, and anxiety grows from thoughts of a future “threat” whose likelihood remains unclear. While depression is defined by a lack of energy, anxiety is perceived as more of a system overload and is tied to excessive concern over the possibility of experiencing harm.

Common anxiety symptoms include nervousness, feelings of panic, increased heart rate, rapid breathing, sweating, insomnia, trembling, and difficulty focusing or thinking clearly.

  • Anxious Depression Demographics: Between 60-90% of patients with depression have moderate to severe anxiety. Anxious depression is linked to greater severity of depression symptoms, higher risk of suicide, reduced response rates to treatment, and higher risk of cardiovascular disease and diabetes.
  • Possible Causes for Anxious Depression: Several neurobiological differences have been observed in patients with anxious depression compared to those with non-anxious depression. This includes white blood cell counts, dysregulation of the hypothalamic-pituitary-adrenal axis, and cortical thinning in the anterior cingulate cortex and insula. Further study is necessary to verify and explore these associations.

Treatment Options in Your Battle Against Anxious Depression

Treatment options for individuals dealing with both anxiety and depression often mirror those utilized for standalone anxiety disorders or major depressive disorder without comorbidity. One innovative non-pharmacological and noninvasive alternative is Deep Transcranial Magnetic Stimulation (Deep TMS), designed to overcome some of the constraints associated with conventional treatment modalities.

Deep TMS involves the application of magnetic pulses to regulate neural activity in specific brain structures. FDA clearance for treating anxious depression was obtained in 2021, marking it as a promising intervention. Deep TMS distinguishes itself through its lack of systemic side effects typical of medications, absence of anesthesia or recovery periods, and proven effectiveness in cases resistant to traditional treatments.

Psychotherapy, encompassing various forms of talk therapy, proves beneficial in addressing anxious depression. Cognitive-Behavioral Therapy (CBT) assists individuals in replacing negative thoughts with constructive patterns of thinking and behavior. Interpersonal Therapy (IPT) focuses on current relationship dynamics to alleviate anxiety and depressive symptoms. Problem-Solving Therapy equips patients with skills to manage stress through identifying barriers, generating creative solutions, and making effective decisions. Despite its efficacy, psychotherapy demands a substantial time commitment and may not suffice for severe cases of anxious depression.

Pharmacological interventions, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs), have demonstrated success in addressing both depression and anxiety symptoms. However, studies indicate that individuals with anxious depression might not sustain symptom improvement post-initial treatment, and they face a heightened risk of side effects like weight gain or sexual dysfunction.

Electroconvulsive therapy (ECT) induces controlled seizures to stimulate neural activity, proving effective in alleviating severe depression. However, its impact on anxiety remains contentious, with conflicting study results showing either limited improvement or exacerbation of symptoms. ECT necessitates full sedation and poses potential side effects such as nausea, confusion, and short-term memory loss.

Adopting lifestyle changes can contribute to managing anxious depression. Establishing stress-reduction habits, including improved sleep patterns, a balanced diet, and regular exercise, proves beneficial. Avoiding substances like alcohol, drugs, and tobacco is crucial, as they can exacerbate symptoms and interfere with other treatment modalities like therapy, medication, or Deep TMS. Lastly, participation in social support groups can create an effective network to alleviate both anxiety and depression symptoms.

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available from 10:00 – 19:00

Address 1840 W 49 ST STE 404 Hialeah, FL 33012


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